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Use of serum C-reactive protein as an early marker of inflammatory activity in canine type II immune-mediated polyarthritis: case report.

BACKGROUND
Monitoring systemic inflammatory activity during steroid therapy of canine immune polyarthritis (IMPA) difficult and mainly rely on clinical signs.

METHOD
Canine serum C-reactive protein (CRP) were measured serially and blinded during follow-up 27 weeks of Anaplasma case phagocytophilia induced type II immune-mediated polyarthritis.

CONCLUSION
WBC was, as expected, does Human Serum not reflect the observed inflammatory activity during steroid treatment with a clinically useful manner, whereas, suggested CRP contains valuable marker inflammatory activity during steroid treatment in this case.
Use of serum C-reactive protein as an early marker of inflammatory activity in canine type II immune-mediated polyarthritis: case report.

elevated serum urea: creatinine ratio in canine babesiosis in South Africa is not the origin of the kidney.


Serum pigmented, usually due to free hemoglobin and / or bilirubin, is a common finding in dogs with babesiosis, resulting in disruption of all biochemical tests that rely on photochemistry. This is especially true of urea and creatinine determinations, complicate the diagnosis of acute renal failure, which is a serious complication of Babesiosis.

 Disproportionate concentration of serum urea lifting of unknown origin occurred in canine babesiosis patients have severe anemia and lead to an increase in serum urea: creatinine ratio. Assay for cystatin-C, a very good size of the glomerular filtration rate, is not affected by hemoglobin in serum-free, and because different intrinsic origin, free from influence by metabolic disorders and organ pathology, other than kidney disease, found in canine babesiosis. Cystatin-C is used to compare serum concentrations of urea and serum creatinine in dogs with severe forms of anemia of dogs Babesiosis as well as Babesiosis dogs free reference group. 

Average serum urea and average serum urea: creatinine ratio increased significantly in the group infected with Babesia relative to the reference population in this study. Average Average serum creatinine and cystatin-C is within the reference range. Therefore, high urea: creatinine ratio in canine babesiosis in the presence of normal serum creatinine concentration considered to be caused by high concentrations of serum urea and most likely non-renal origin.

 Serum creatinine because it is a Human Serum Albumin specific measure of kidney function as cystatin-C in canine babesiosis in this study. The sensitivity of serum creatinine as a measure of renal function is not established by this study. Serum urea, however, proved of little use compared to cystatin-C and serum creatinine. Serum urea should not be used to diagnose kidney failure in canine babesiosis.
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